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Medical Checkup

AURA

Trial Enrolment Status

OPEN

Disease Under Study

Idiopathic Pulmonary Fibrosis

Duration

12 weeks

About the Trial

This study will evaluate the impact Nintedanib Solution for Inhalation (AP02) has on lung function and key measures of fibrosis in adult patients with idiopathic pulmonary fibrosis (IPF) as well as assess its safety and tolerability.

Adults 40 years of age or older with IPF who meet the inclusion and exclusion criteria can participate in this study if they are not currently on treatment for IPF, and if treated with oral nintedanib or pirfenidone, have stopped the medication for at least 3 months.

Researchers will compare two different doses of AP02 to a placebo (a look-alike substance that contains no drug) to see if AP02 works to treat IPF. Participants are put into 1 of 3 groups randomly, which means by chance and will take AP02 or a placebo two times every day for 12 weeks by using a nebulizer, which is a device that provides medicine to the lungs via inhalation

Mechanism of Action:

Duration of Study

12 weeks

Phase

II

Principal Investigator

Dr. George Philteos

Sub-Investigator

Dr. Anushya Chelvanathan

Study Coordinator

Cynthia Lee

Durham Institute of Respirology | Dynamic Drug Advancement Ltd

Address:

Hours:

601 Harwood Avenue South, Suite 201

Ajax, Ontario L1S 2J5

M-F:

9:00am - 5:00pm

Closed on statutory holidays

Main Office Phone: 

 

 

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Main Office Fax:   

Clinical Trial Phone:

Clinical Trial Fax: 

Dr. Chelvanathan: (905) 239 0225

Dr. Franco: (905) 239 0221

Dr. O'Loghlen: (905) 239 0221

Dr. Philteos: (905) 427 1419

(905) 427-0346

(365) 885-9086

(905) 239-0056

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